ChemicalBook > CAS DataBase List > Sanggenon C
Sanggenon C
- Product Name
- Sanggenon C
- CAS No.
- 80651-76-9
- Chemical Name
- Sanggenon C
- Synonyms
- sanggenone;Sanggenon C;Sanggenone C;2-[(1S,5S,6R)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-1,3,8,10a-tetrahydroxy-5a-(3-methylbut-2-enyl)-[1]benzofuro[3,2-b]chromen-11-one;2-[(1S)-6β-(2,4-Dihydroxybenzoyl)-5α-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexene-1β-yl]-5a,10a-dihydro-1,3,8,10aβ-tetrahydroxy-5aβ-(3-methyl-2-butenyl)-11H-benzofuro[3,2-b][1]benzopyran-11-one;(5aR,10aS)-2-[6β-(2,4-Dihydroxybenzoyl)-5α-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexene-1β-yl]-5a,10a-dihydro-1,3,8,10a-tetrahydroxy-5a-(3-methyl-2-butenyl)-11H-benzofuro[3,2-b][1]benzopyran-11-one;(5aR,10aS)-2-[(1S,5S,6R)-6-(2,4-Dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-5a,10a-dihydro-1,3,8,10a-tetrahydroxy-5a-(3-methyl-2-buten-1-yl)-11H-benzofuro[3,2-b][1]benzopyran-11-one;11H-Benzofuro[3,2-b][1]benzopyran-11-one, 2-[(1S,5S,6R)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-5a,10a-dihydro-1,3,8,10a-tetrahydroxy-5a-(3-methyl-2-buten-1-yl)-, (5aR,10aS)-;(5aR,10aS)-2-((1S,2R,3S)-2-(2,4-Dihydroxybenzoyl)-2',4'-dihydroxy-5-methyl-1,2,3,6-tetrahydro-[1,1'-biphenyl]-3-yl)-1,3,8,10a-tetrahydroxy-5a-(3-methylbut-2-en-1-yl)-5a,10a-dihydro-11H-benzofuro[3,2-b]chromen-11-one
- CBNumber
- CB01252426
- Molecular Formula
- C40H36O12
- Formula Weight
- 708.71
- MOL File
- 80651-76-9.mol
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Sanggenon C Property
- Melting point:
- > 240°C (dec.)
- Boiling point:
- 995.5±65.0 °C(Predicted)
- Density
- 1.512
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- Acetone (Slightly), Methanol (Slightly)
- pka
- 6.61±0.60(Predicted)
- form
- Solid
- color
- Yellow
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 30061
- Product name
- Sanggenone C
- Packaging
- 1mg
- Price
- $117
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 30061
- Product name
- Sanggenone C
- Packaging
- 10mg
- Price
- $923
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 30061
- Product name
- Sanggenone C
- Packaging
- 5mg
- Price
- $521
- Updated
- 2024/03/01
TRC
- Product number
- S112545
- Product name
- SanggenoneC
- Packaging
- 2.5mg
- Price
- $220
- Updated
- 2021/12/16
Usbiological
- Product number
- 300919
- Product name
- Sanggenon C
- Packaging
- 20mg
- Price
- $623
- Updated
- 2021/12/16
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Sanggenon C Chemical Properties,Usage,Production
Description
Sanggenone C is a flavonoid that has been found in mulberry bark and has diverse biological activities. It inhibits TNF-α- or IL-1β-induced polymorphonuclear leukocyte (PMN) adhesion to human synovial cells (HSCs; IC50s = 27.29 and 54.43 nM, respectively), as well as inhibits NF-κB activation in HSCs. Sanggenone C induces apoptosis and production of reactive oxygen species (ROS) in HT-29 cells when used at concentrations ranging from 10 to 40 μM. It decreases cell viability of HT-29 cells in vitro and reduces tumor growth in an HT-29 mouse xenograft model when administered at a dose of 10 mg/kg. Sanggenone C increases vertebrate column bone mineralization in a zebrafish model of prednisone-induced osteoporosis. It also attenuates cardiac hypertrophy and fibrosis and reduces activation of nuclear factor of activated T cells 2 (NFAT2) in a mouse model of pressure overload-induced cardiac hypertrophy.
Uses
Sanggenone C is a flavanone isolated from Morus plant that showed cytotoxicity against human oral tumor cell lines (HSC-2 and HSG). Sanggenone C is also an inhibitor of protein tyrosine phosphatase 1B.
Definition
ChEBI: Sanggenon C is a diarylheptanoid.
target
NF-kB | NO | NOS | IkB | IKK
Sanggenon C Preparation Products And Raw materials
Raw materials
Preparation Products
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Sanggenon C Suppliers
- Tel
- 702-983-3769
- Fax
- 702-983-3769
- sales@albtechnology.com
- Country
- United States
- ProdList
- 2993
- Advantage
- 55
- Tel
- 888-539-0666
- Fax
- 888-539-0666
- info@emmx.com
- Country
- United States
- ProdList
- 8449
- Advantage
- 60
- Tel
- +1-781-999-5354
- support@targetmol.com
- Country
- United States
- ProdList
- 19973
- Advantage
- 58
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View Lastest Price from Sanggenon C manufacturers
Shaanxi Haibo Biotechnology Co., Ltd
- Product
- Sanggenon C 80651-76-9
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000ton
- Release date
- 2023-09-01
Shanghai Standard Technology Co., Ltd.
- Product
- Sanggenon C 80651-76-9
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-03-12
Career Henan Chemical Co
- Product
- Sanggenon C 80651-76-9
- Price
- US $100.00/KG
- Min. Order
- 1KG
- Purity
- 97%
- Supply Ability
- customise
- Release date
- 2018-07-26
80651-76-9, Sanggenon CRelated Search:
Mulberroside B
Sanggenol P
3-N-OXALYL-L-2,3-DIAMINOPROPANOICACID
Cornuside
Alpinetin
KAEMPFEROL-3-O-RUTINOSIDE
SHANZHISIDE METHYL ESTER
spicatosideB
Complanatoside A
Maslinic acid
SAUCHINONE
7,8-Dihydroxycoumarin
ARTEMISININ
MORIN
Cephalomannine
Notoginsenoside R1
kuwanon H
mulberrofuran G